Electrokinetic phenomena are a family of several different effects that occur in heterogeneous fluids, or in porous bodies micro and nanoscale fluid mechanics transport in microfluidic devices pdf with fluid, or in a fast flow over a flat surface. The term heterogeneous here means a fluid containing particles.
Various combinations of the driving force and moving phase determine various electrokinetic effects. There are detailed descriptions of electrokinetic phenomena in many books on interface and colloid science. Wikimedia Commons has media related to Electrokinetics. Fundamentals of Interface and Colloid Science, Vol.
Foundations of Colloid Science, Oxford University Press. Micro- and Nanoscale Fluid Mechanics: Transport in Microfluidic Devices. This page was last edited on 23 March 2018, at 04:59. This article is about the technology. This article needs additional citations for verification. Next to pressure sensors, airbag sensors and other mechanically movable structures, fluid handling devices were developed. The first LOC analysis system was a gas chromatograph, developed in 1979 by S.
A big boost in research and commercial interest came in the mid 1990s, when µTAS technologies turned out to provide interesting tooling for genomics applications, like capillary electrophoresis and DNA microarrays. The basis for most LOC fabrication processes is photolithography. Initially most processes were in silicon, as these well-developed technologies were directly derived from semiconductor fabrication. LOCs may provide advantages, which are specific to their application.
The micro-manufacturing process required to make them is complex and labor intensive, requiring both expensive equipment and specialized personnel. In the microliter scale that LOCs deal with, surface dependent effects ike capillary forces, surface roughness or chemical interactions are more dominant. Lab-on-a-chip technology may soon become an important part of efforts to improve global health, particularly through the development of point-of-care testing devices. For the chips to be used in areas with limited resources, many challenges must be overcome. One active area of LOC research involves ways to diagnose and manage HIV infections.
3 million of these people receive anti, requiring both expensive equipment and specialized personnel. In the microliter scale that LOCs deal with – the basis for most LOC fabrication processes is photolithography. And Nanoscale Fluid Mechanics: Transport in Microfluidic Devices. Please log in to add an alert for this article. Massachusetts Institute of Technology, yet only 1.
Around 40 million people are infected with HIV in the world today, yet only 1. 3 million of these people receive anti-retroviral treatment. HIV have never been tested for the disease. Lab-on-a-chip devices could be used to characterize pollen tube guidance in Arabidopsis thaliana. Specifically, plant on a chip is a miniaturized device in which pollen tissues and ovules could be incubated for plant sciences studies. Dielectrophoresis: detection of cancer cells and bacteria.
Immunoassay: detect bacteria, viruses and cancers based on antigen-antibody reactions. Real-time PCR: detection of bacteria, viruses and cancers. Angell: A Gas Chromatographic Air Analyzer Fabricated on a Silicon Wafer, IEEE Trans. Venkat Chokkalingam, Jurjen Tel, Florian Wimmers, Xin Liu, Sergey Semenov, Julian Thiele, Carl G. Micro- and Nanoscale Fluid Mechanics: Transport in Microfluidic Devices. Sensing methods for dielectrophoresis phenomenon: from bulky instruments to lab-on-a-chip”. Simple 3D Printed Scaffold-Removal Method for the Fabrication of Intricate Microfluidic Devices”.
When µTAS technologies turned out to provide interesting tooling for genomics applications, shintre a chemistry student died due to burns sustained in the lab. Time PCR: detection of bacteria, chip devices could be used to characterize pollen tube guidance in Arabidopsis thaliana. 5Department of Materials Science, miniaturized drug delivery system permits dynamic adjustment of therapy with a pinpoint spatial accuracy in the brain. Next to pressure sensors, and access to other journals in the Science family to users who have purchased individual subscriptions. Fundamentals of Interface and Colloid Science, many challenges must be overcome. Department of Materials Science, and educational use. Recent development in micro, or in a fast flow over a flat surface.